CAS RN 1374601-40-7

IUPAC Name: —

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Molecular Weight (g/mol): —

Molecular Formula: —

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Grade

Molecular Weight (g/mol)

Percent Purity

Physical Form

Quantity

MedChemExpress BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 μM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	413.47
Color	White
Physical Form	Powder
Chemical Name or Material	BRD4770
Grade	Research
SMILES	O=C(C1=CC=C2C(N=C(NC(C3=CC=CC=C3)=O)N2CCCC4=CC=CC=C4)=C1)OC
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.59%
CAS	1374601-40-7
Solubility Information	DMSO : 33.33 mg/mL (80.61 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₂₃N₃O₃
Formula Weight	413.47

CAS RN 1374601-40-7

CAS RN 1374601-40-7

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