CAS RN 1575818-46-0

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PRN694, MedChemExpress

MedChemExpress PRN694 is an irreversible, highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0.3 nM and 1.4 nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	543.67
Color	Light Brown
Physical Form	Powder
Chemical Name or Material	PRN694
Grade	Research
SMILES	O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[C@@H](C)C(C)(C)C)=CC=C3N2C[C@@H]4N(C(C=C)=O)CCC4
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.0%
CAS	1575818-46-0
Solubility Information	DMSO : 125 mg/mL (229.92 mM; Need ultrasonic and warming)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₃₅F₂N₅O₂S
Formula Weight	543.67

CAS RN 1575818-46-0

CAS RN 1575818-46-0

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