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  6. Thermo Scientific Chemicals 5-Azacytidine, 99%

Thermo Scientific Chemicals 5-Azacytidine, 99%

Catalog Number p-61545
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Quantity:
50 mg
1 g
Este artículo no se puede devolver. Vea la política de devoluciones
320-67-2
C8H12N4O5
244.21
MFCD00006539
NMUSYJAQQFHJEW-KVTDHHQDSA-N
5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
9444
CHEBI:2038
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Este artículo no se puede devolver. Vea la política de devoluciones
320-67-2
C8H12N4O5
244.21
MFCD00006539
NMUSYJAQQFHJEW-KVTDHHQDSA-N
5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
9444
CHEBI:2038
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Descripción

5-Azacytidine, CAS # 320-67-2, is an chemical analog of cytidine that acts as an inhibitor of DNA methyltransferase activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
5-Azacytidine is a chemical analog of the nucleoside cytidine that incorporates into DNA and inhibits DNA methylation
At low doses, 5-azacytidine irreversibly binds the enzyme DNA methyltransferase (DNMT)
Applications
5-Azacytidine has been used for cardiomyocyte differentiation from mesenchymal stem cells
It has been used as a potent DNMT inhibitor in the study of tumor cell proliferation and induction of gene expression following demethylation
5-Azacytidine can globally change histone modification patterns
TRUSTED_SUSTAINABILITY
CAS Min % 98.5
CAS Max % 100.0
Melting Point 228.0°C to 230.0°C
Color White
Infrared Spectrum Authentic
Assay Percent Range 98.5% min. (HPLC)
Packaging Glass bottle
Quantity 50 mg
Merck Index 15, 884
Specific Rotation + 40.00
Solubility Information Solubility in water: .. Other solubilities: soluble in methanol
Formula Weight 244.21
Percent Purity 99%
Physical Form Crystalline Powder
Chemical Name or Material 5-Azacytidine, 99%
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Seguridad y manipulación

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Nombre del producto
  • 5-Azacytidine
 Palabra de advertencia
  • Danger
 Clasificación
  • Acute toxicity Category 4
  • Germ cell mutagenicity Category 1B
 Indicaciones de peligro
  • H340-May cause genetic defects.
  • H302-Harmful if swallowed.
 Consejos de prudencia
  • P201-Obtain special instructions before use.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only

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