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![ABL1 [E255K] Recombinant Human Protein, Invitrogen™ 10μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
ABL1 [E255K] Recombinant Human Protein, Invitrogen™
ABL1 [E255K] Recombinant Human Protein
Brand: Invitrogen PV3864
Additional Details : Weight : 0.05250kg
Description
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The E255K mutant is a Gleevec resistant form of ABL1.Specifications
| NP_005148.2, E255K | |
| Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 125.4kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| ABL1 E255K, ABL, c-ABL | |
| ABL1 E225K was pre-diluted in enzyme dilution buffer and assayed in 50mM Tris (pH 7.5), 10mM MgCl2, 1mM DTT, 0.01% NP-40, 200μM ATP, 333μg/mL Abl1 peptide substrate (EAIYAAPFAKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| E255K | |
| 490nmoles of phosphate transferred to Abl1 peptide substrate (EAIYAAPFAKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1.67μg/mL | |
| His Tag | |
| Kinase and inhibitors | |
| 50% by SDS-PAGE |
| 0.35mg/mL | |
| 25, 7376 | |
| ABL1 [E255K] Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| ABL1 [E255K] Recombinant Human Protein | |
| ABL | |
| ABL1 [E255K] Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Cytoplasmic tyrosine kinase |
For Research Use Only. Not for use in diagnostic procedures.