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Complement C4 Mouse anti-Human, Clone: 49H9, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen LFMA0188

Additional Details : Weight : 0.99000kg

Product Code. 10191020

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Description

Description

A suggested positive control for this product is human plasma.

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
Specifications

Specifications

Complement C4
Monoclonal
Unconjugated
P0C0L4
C4A
Protein purified from Human plasma
100 μL
Primary
Human
Antibody
IgG2b
ELISA, Immunoprecipitation, Western Blot
49H9
C4A
DAMC-258G8.6, C4, C4A2, C4A3, C4A4, C4A6, C4S, CO4, CPAMD2, MGC164979, RG
Mouse
Ammonium sulfate precipitation
RUO
720
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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