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  6. Invitrogen™ CES1 Recombinant Mouse Monoclonal Antibody (K1E067_8D1)

Invitrogen™ CES1 Recombinant Mouse Monoclonal Antibody (K1E067_8D1)

Product Code. 30830384
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30830384 50 μL
30827829 100 μL
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Product Code. 30830384 Supplier Invitrogen™ Supplier No. MA565944

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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: GAPTYMYEFQ YRPSFSSDMK PKTVIGDHGD ELFSVFGAPF LKEGASEEEI RLSKMVMKFW ANFARNGNPN GEGLPHWPEY NQKEGYLQIG ANTQAAQKLK DKEVAFWTNL FAKKAVEKPP Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 80%, Pig - 77%, Cynomolgus monkey - 98%.

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CES1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K1E067_8D1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide
Gene CES1
Gene Accession No. P23141
Gene Alias ACAT; acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; carboxyesterase ES-3; carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 1A; carboxylesterase 1E; Carboxylesterase 1G; carboxylesterase 1-like; carboxylesterase 2 (liver); CE-1; CEH; Ces1; Ces-1; Ces1a; Ces1e; Ces1g; Ces1l; CES2; cholesteryl ester hydrolase; cocaine carboxylesterase; Eg; EG244595; Egasyn; Es22; Es-22; ES-HTEL; esterase 22; esterase-22; ES-x; Gm4976; hCE-1; HMSE; HMSE1; human monocyte/macrophage serine esterase 1; liver carboxylesterase 1; Liver carboxylesterase 22; liver carboxylesterase 3; methylumbelliferyl-acetate deacetylase 1; MGC117365; Monocyte/macrophage serine esterase; PCE-1; pI 5.5 esterase; REH; Retinyl ester hydrolase; serine esterase 1; SES1; Ses-1; TGH; triacylglycero; Triacylglycerol hydrolase
Gene Symbols CES1
Host Species Mouse
Immunogen Recombinant human CES1 (aa 441-560).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1066
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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