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Ki20227, MedChemExpress

Product Code. p-200098000
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Quantity:
2 mg
5 mg
10 mg
50 mg
Unit Size:
10mg
2mg
50mg
5mg
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Product Code. 16490307

Brand: Medchem Express HY10408

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Description

MedChemExpress Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction.

Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction.

Specifications

Chemical Name or Material Ki20227
CAS 623142-96-1
Color Brown
Purity Grade Notes Research
Molecular Formula C24H24N4O5S
Quantity 50 mg
Solubility Information DMSO : 62.5 mg/mL (130.06 mM; Need ultrasonic)
SMILES O=C(NC1=CC=C(C=C1OC)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC(C)C4=NC=CS4
Molecular Weight (g/mol) 480.54
Formula Weight 480.54
Percent Purity 98.05%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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