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Invitrogen™ PLSCR1 Recombinant Rabbit Monoclonal Antibody (24GB1550)
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Rabbit Recombinant Monoclonal Antibody

198.00 € - 564.00 €

Specifications

Antigen PLSCR1
Clone 24GB1550
Content And Storage -20°C
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30275657
GREENER_CHOICE
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Invitrogen™
MA557580
100 μL
564.00 €
100µL
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30274905
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Invitrogen™
MA557581
20 μL
198.00 €
20µL
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Description

Description

PLSCR1 Recombinant Monoclonal Antibody for Western Blot, Flow

The calcium-dependent plasma membrane protein phospholipid scramblase 1 (PLSCR1) contributes to the transbilayer movement of phosphatidylserine and other membrane phospholipids upon influx of calcium into the cytosol. This movement results in plasma membrane phospholipid remodelling and surface exposure of phosphatidylserine in injured or apoptotic cells, which leads to cell death. Interferons and other cytokines induce expression of PLSCR1, implying that PLSCR1 also functions in cytokine signaling pathways. EGF stilmulation results in tyrosine phosphorylation of PLSCR1 on tyrosines 69 and 74, which allows it to interact with Shc, and thereby connecting Src kinase activation to stimulation of the EGF receptor.
Specifications

Specifications

PLSCR1
-20°C
Recombinant Monoclonal
Liquid
IgG
Human, Mouse, Rat
PLSCR1
ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1a; MmTRA1b; NOR1; Phospholipid scramblase 1; phospholipid scramblase 2; PL scramblase 1; Plscr1; Tra1; Tra1a; Tra1b; transplantability-associated protein 1; Tras1; Tras2
PLSCR1
Primary
Affinity chromatography
24GB1550
Flow Cytometry, Western Blot, Immunocytochemistry
Unconjugated
Rabbit
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O15162, P58195, Q9JJ00
117540, 22038, 5359
A synthesized peptide derived from human Scramblase 1 (aa 20-55).
Antibody
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