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Invitrogen™ Rat CD-80 ELISA Kit
Rat CD-80 quantitates rat CD-80 in serum, plasma, supernatant.
Brand: Invitrogen™ ERA6RBX5
Additional Details : Weight : 0.33800kg
Description
Rat CD-80 quantitates rat CD-80 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat CD-80.
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.Specifications
| Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1 | |
| 1.23 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 5 x 96 Tests | |
| Plasma, 50 μL; Supernatant, 50 μL; Serum, 50 μL | |
| CD80 (B7-1) | |
| 4 hr 45 min |
| 1.23 to 300 ng/mL | |
| Biotin | |
| Plasma, Serum, Supernatant | |
| CD80 | |
| <10% | |
| HRP | |
| Research Use Only | |
| 2°C to 8°C | |
| 1 hr 20 min |