A collection of genes utilized by the RNA interference (RNAi) pathway; the RNAi pathway is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. Ideal for genetic screening.
The Silencer™ Select Human Cancer Genome siRNA Library contains 1596 Invitrogen™ Silencer Select siRNAs targeting 532 gene targets that are commonly affected in cancers.
The Invitrogen™ LentiArray™ Human Cell Surface Protein Library targets 778 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 3,112 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous.
DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.
The Silencer Human Drug Targets siRNA Library contains 23,745 Invitrogen™ Silencer siRNAs targeting 7,915 genes for performing RNAi screens against known human drug target genes.
The Invitrogen™ LentiArray™ Human Nuclear Hormone Receptor Library targets 47 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 188 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
Targets 446 genes with up to 4 gRNA per gene target for a total of 1,784 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
Targets 141 genes with up to 4 gRNA per gene target for a total of 564 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus