A collection of genes utilized by the RNA interference (RNAi) pathway; the RNAi pathway is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. Ideal for genetic screening.
The Invitrogen™ LentiArray™ Human Cancer Biology Library targets 510 genes commonly involved in the development of cancer with up to 4 gRNA per gene target (pooled in a single well) for a total of 2,040 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
The Invitrogen™ LentiArray™ Human Phosphatase Library targets 288 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 1,152 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
The Invitrogen™ LentiArray™ Human Tumor Suppressor Library targets 716 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 2,864 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
Targets 1,444 genes with up to 4 gRNA per gene target for a total of 5,776 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
Targets 1,817 genes with up to 4 gRNA per gene target for a total of 7,268 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus
The Silencer™ Select Human Apoptosis siRNA Library provides investigators with a focused siRNA screening platform targeting apoptosis genes and enabling a detailed analysis of the apoptotic signaling pathway.
Targets 561 genes with up to 4 gRNA per gene target for a total of 2,244 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus
The Silencer™ Human Druggable Genome siRNA Library targets genes in the known druggable genome for performing RNAi functional screens for potential therapeutic targets.
Silencer™ siRNA Libraries feature combinations of Silencer™ Pre-designed siRNAs, and when available, Silencer™ Validated siRNAs, in 96-well or 384-well plates.
Targets 475 genes with up to 4 gRNA per gene target for a total of 1,900 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
Ion channels are key components in a multitude of biological processes, including rapid changes in muscle cell contractions, epithelial transport of nutrients and ions, T cell activation and pancreatic beta-cell insulin release.