CAS RN 1630086-20-2

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MedChemExpress Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

Molecular Weight (g/mol)	601.12
Color	Light Yellow
Physical Form	Powder
Chemical Name or Material	Kira8
Grade	Research
SMILES	O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O
For Use With (Application)	COVID-19-anti-virus
Percent Purity	98.02%
CAS	1630086-20-2
Solubility Information	DMSO : 65 mg/mL (108.13 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	AMG-18
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₁H₂₉ClN₆O₃S
Formula Weight	601.12