CAS RN 869886-67-9

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Ulixertinib, MedChemExpress

MedChemExpress Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.

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Specifications

Molecular Weight (g/mol)	433.33
Color	White
Physical Form	Solid
Chemical Name or Material	Ulixertinib
Grade	Research
SMILES	O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.44%
CAS	869886-67-9
Solubility Information	DMSO : 100 mg/mL (230.77 mM; Need ultrasonic)
Synonym	BVD-523 VRT752271
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₂₂Cl₂N₄O₂
Formula Weight	433.33

CAS RN 869886-67-9

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