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1,3-Dichloroacetone, 96%
Description
1,3-Dichloroacetone is used in the synthesis of citric acid. It is used as a solvent and as an intermediate in organic synthesis. Further, it serves as an acceptor substrate in the cross-aldol reaction with donor substrates such as acetone, cyclopentanone and cyclohexanone. It is also used in the preparation of an active pharmaceutical ingredient, famotidine.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
1,3-Dichloroacetone is used in the synthesis of citric acid. It is used as a solvent and as an intermediate in organic synthesis. Further, it serves as an acceptor substrate in the cross-aldol reaction with donor substrates such as acetone, cyclopentanone and cyclohexanone. It is also used in the preparation of an active pharmaceutical ingredient, famotidine.
Solubility
Soluble in water, ethanol and diethyl ether.
Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents, strong bases and reducing agents.
Specifications
Specifications
| Melting Point | 40°C to 44°C |
| Density | 1.383 |
| pH | 4.2 |
| Boiling Point | 172°C to 173°C |
| Flash Point | 95°C (203°F) |
| Odor | Pungent |
| Refractive Index | 1.44 |
| Quantity | 25 g |
| UN Number | UN2649 |
| Beilstein | 605456 |
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Safety and Handling
- Danger
- Acute toxicity Category 1
- Acute toxicity Category 2
- Acute toxicity Category 3
- Serious eye damage/eye irritation Category 1
- Germ cell mutagenicity Category 2
- Skin corrosion/irritation Category 1 B
- H300-Fatal if swallowed.
- H311-Toxic in contact with skin.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H330-Fatal if inhaled.
- H341-Suspected of causing genetic defects.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
RUO – Research Use Only
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