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  5. Tocris Bioscience™ LY 2603618

Tocris Bioscience™ LY 2603618
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Product Code. 18797976
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18797976

Brand: Tocris Bioscience™ 6454/10

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Description

Potent and selective Chk1 inhibitor (IC50 = 7 nM)

LY 2603618 is a potent and selective Chk1 inhibitor (IC50 = 7 nM). Inhibits Chk1 autophosphorylation. Induces cell cycle arrest in the G2/M phase and induces the DNA damage response in lung cancer cells. Inhibits growth of NSCLC xenografts in mice when administered in combination with Pemetrexed (Cat.No. 6185).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy)phenyl]-N'-(5-methyl-2-pyrazinyl)urea
CAS 911222-45-2
Quantity 10 mg
Molecular Formula C18H22BrN5O3
Formula Weight 436.3
Purity 98%
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