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Tocris Biosciences™ SU 5402

Product Code. 30448874
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10 mg
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Product Code. 30448874

Brand: Tocris Biosciences™ 3300/10

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This item is not returnable. View return policy

Description

Potent FGFR and VEGFR inhibitor

SU 5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively). Inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo. Also attenuates integrin β4-induced differentiation of neural stem cells. Supports mESC self-renewal.

For more information about how SU 5402 may be used, see our protocol: Accelerated Induction of Cortical Neurons from hiPSCs

TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid
CAS 215543-92-3
Quantity 10 mg
Target FGF Receptor Inhibitors
Molecular Formula C17H16N2O3
Purity 0.95
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