missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18013922

Tocris Bioscience™ 2-Deoxy-D-glucose

Product Code. 18013922
Change view
Click to view available options
Quantity:
50 mg
Unit Size:
50mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18013922 50 mg 50mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 18013922 Supplier Tocris Bioscience™ Supplier No. 4515/50

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Non-metabolizable glucose analog; hexokinase substrate

2-Deoxy-D-glucose is a non-metabolizable glucose analog. Inhibits phosphorylation of glucose by hexokinase; causes depletion of cellular ATP. Also inhibits phosphoglucose isomerase (PGI) competitively. Causes cell cycle inhibition and cell death in in vitro models of hypoxia; blocks tumor cell growth in animal models. Also shown to induce the unfolded protein response (UPR). 2-Deoxy-D-glucose disrupts N-glycan expression on the surface of pancreatic adenocarcinoma cells. 2-Deoxy-D-glucose enhances chimeric antigen receptor T cell activity in different xenograft mouse models of pancreatic adenocarcinoma cells.
TRUSTED_SUSTAINABILITY

Specifications

CAS 154-17-6
Quantity 50 mg
Molecular Formula C6H12O5
Formula Weight 164.16
Purity >98%
Molecular Weight (g/mol) 164.16
Chemical Name or Material 2-Deoxy-D-glucose
Titolo del prodotto
Selezionare un problema

Facendo clic su Invia, l'utente riconosce che potrebbe essere contattato da Fisher Scientific in merito al feedback fornito in questo modulo. Non condivideremo le vostre informazioni per altri scopi. Tutte le informazioni di contatto fornite saranno conservate in conformità con la nostra Politica sulla privacy. Informativa sulla privacy.