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2-Mercaptopyridine N-oxide, 99%

Product Code. 11428136
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Product Code. 11428136 Supplier Thermo Scientific Alfa Aesar Supplier No. A14152.22
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CAS: 1121-31-9 | C5H5NOS | 127.161 g/mol

2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

Solubility
Soluble in tris-hydrochloric acid.

Notes
Incompatible with strong oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1121-31-9
Molecular Formula C5H5NOS
Molecular Weight (g/mol) 127.161
MDL Number MFCD00006196
InChI Key YBBJKCMMCRQZMA-UHFFFAOYSA-N
Synonym pyrithione, 2-mercaptopyridine n-oxide, 2-mercaptopyridine-n-oxide, 1-hydroxy-2-pyridinethione, omadine, 2-pyridinethiol, 1-oxide, 1-hydroxyl-1h-pyridine-2-thione, n-hydroxypyridine-2-thione, 1-hydroxy-2 1h-pyridinethione, 2-pyridinethiol 1-oxide
PubChem CID 1570
ChEBI CHEBI:36578
IUPAC Name 1-hydroxypyridine-2-thione
SMILES C1=CC(=S)N(C=C1)O

Specifications

Melting Point 69°C to 72°C
Quantity 100 g
Beilstein 906983
Sensitivity Air and light sensitive
Merck Index 14,7994
Solubility Information Soluble in tris-hydrochloric acid.
Formula Weight 127.17
Percent Purity 99%
Chemical Name or Material 2-Mercaptopyridine N-oxide

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