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  5. Thermo Scientific™ TheraPure™ 2'-MOE-5mC Phosphoramidite, serum vial bottle

Thermo Scientific™ TheraPure™ 2'-MOE-5mC Phosphoramidite, serum vial bottle

Product Code. 18084090 Shop All Thermo Scientific Products
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18054060 5 g 5g
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Product Code. 18084090 Supplier Thermo Scientific™ Supplier No. 27102002
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Beskrivning

2'-MOE-5mC CEP is a phosphoramidite containing 5' DMT and the nucleoside 5-methyl-cytidine (5mC) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis.

2'-MOE-5mC CEP is a phosphoramidite containing 5' DMT and the nucleoside 5-methyl-cytidine (5mC) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methoxy-ethyl (MOE) modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.

Features:

  • Full chemical name – 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-N4-benzoyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula – C50H60N5O10P
  • Base—5mC
  • Base Protection – Bz
  • Molecular weight – 922.0 g/mol
  • CAS number – 163759-94-2
  • HPLC purity – ≥99%; M-11 Impurity ≤0.01%
  • 31P NMR purity – ≥99%
TRUSTED_SUSTAINABILITY

Specifikationer

For Use With (Equipment) AKTA Synthesizers, Applied Biosystems Synthesizers
Product Type 2in-MOE-5mC CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Cytidine (C)
Reagent Features 2in-MOE modified
Shipping Condition Room Temperature
Purity 99%
Quantity 1 g
Reagent Type Phosphoramidite
Grade TheraPure™
Nucleic Acid Type RNA
Product Line TheraPure
Form Powder
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