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Thermo Scientific™ 2'-OMe-PAC-A Phosphoramidite, standard grade, 20-400 finish bottle

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Quantity:
1 g
Unit Size:
1g
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Product Code. 17927132

Brand: Thermo Scientific™ 27182210

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Description

2'-OMe-PAC-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-PAC-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-O-methyl-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C49H56N7O9P
• Base: A
• Base Protection: PAC
• Formula weight: 918.0 g/mol
• CAS number: 128219-82-9
• HPLC purity: ≥98.0%
• 31P NMR purity: ≥98.0%

TRUSTED_SUSTAINABILITY

Specifications

For Use With (Equipment) Expedite Synthesizers
Product Type 2in-OMe-PAC-A CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Adenosine (A)
Reagent Features 2in-OMe modified, Fast deprotection
Shipping Condition Room Temperature
Purity 98%
Quantity 1 g
Reagent Type Phosphoramidite
Grade Standard
Nucleic Acid Type RNA
Form Powder
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For Research Use Only. Not for use in diagnostic procedures.

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