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  7. 3-Isobutyl-1-Methylxanthine, MP Biomedicals™

3-Isobutyl-1-Methylxanthine, MP Biomedicals™

Product Code. 11495222 Shop All MP Biomedicals Products
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Product Code. 11495222 Supplier MP Biomedicals Supplier No. 02195262.2

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Beschreibung

Known as IBMX. 3-Isobutyl-1-Methylxanthine, MP Biomedicals is a potent, non-specific inhibitor of cAMP and cGMP phosphodiesterases, significantly more effective than theophylline. This inhibition activates PKA, leading to decreased proliferation, increase

A non-specific inhibitor of adenosine 3',5'-cyclic monophosphate phosphodiesterase (cAMP PDE)4, significantly more effective than theophylline. Also inhibits cGMP phosphodiesterases. IBMX inhibits cyclic nucleotide PDE with subsequent inhibition of cyclic nucleotide hydrolysis, resulting in accumulation of cyclic AMP and guanosine 3',5'-cyclic monophosphate.

  • Inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50: 1.3μM)
  • Serves as an adenosine receptor antagonist
  • Inhibits ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells
  • Induces calcium release from intracellular stores in sensory neurons
  • Inhibits the growth of carcinoma cells both in vivo and in vitro in mice
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 28822-58-4
Molecular Formula C10H14N4O2
Molecular Weight (g/mol) 222.25
MDL Number MFCD00005584
InChI Key APIXJSLKIYYUKG-UHFFFAOYSA-N
Synonym 3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine
PubChem CID 3758
ChEBI CHEBI:43253
IUPAC Name 1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
SMILES CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O

Spezifikation

Melting Point 195°C to 202°C
Quantity 250 mg
Formula Weight 222.25
Physical Form Powder

Sicherheit und Handhabung

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Produktidentifikator
  • 3-Isobutyl-1-methylxanthine
 Signalwort
  • Warning
 Gefahrenkategorie
  • Acute toxicity Category 4
 Gefahrenhinweis
  • H302-Harmful if swallowed.
 Sicherheitshinweis
  • P264-Wash thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P330-Rinse mouth.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Ergänzende Informationen
  • MIXTURE LIST-Contain: 3-Isobutyl-1-methylxanthine
Name des Produkts
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