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  5. Tocris Bioscience™ 680C91

Tocris Bioscience™ 680C91
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Product Code. 18757596
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18757596 5 mg 5mg
18727826 25 mg 25mg
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Product Code. 18757596 Supplier Tocris Bioscience™ Supplier No. 4392/5

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122.40 EUR valid until 2026-03-31
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Description

Potent and selective tryptophan 2,3-dioxygenase (TDO) inhibitor

680C91 is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) (Ki = 51 nM). Exhibits no activity against indoleamine 2,3-dioxygenase, monoamine oxidase A and B, 5-HT uptake or 5-HT1A, 1D, 2A and 2C receptors. Produces large increases in brain tryptophan and serotonin in vitro and in vivo in the rat.
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Specifications

Chemical Name or Material 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole
CAS 163239-22-3
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C15H11FN2
Formula Weight Observed MW: 238.26
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