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  7. 7-Chlorokynurenic acid, MedChemExpress

7-Chlorokynurenic acid, MedChemExpress

Product Code. 16494456
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Product Code. 16494456 Supplier Medchem Express Supplier No. HY100811

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Description

MedChemExpress 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery.

7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery.

Specifications

Chemical Name or Material 7-Chlorokynurenic acid
CAS 18000-24-3
Color Off-White
Purity Grade Notes Research
Molecular Formula C10H6ClNO3
Quantity 100 mg
Synonym 7-CKA
Solubility Information DMSO : 16.67 mg/mL (74.55 mM; Need ultrasonic) ∣H2O : 1 mg/mL (4.47 mM; Need ultrasonic)
SMILES O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)O
Molecular Weight (g/mol) 223.61
Formula Weight 223.61
Percent Purity 99.13%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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