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  5. Tocris Bioscience™ A 196

Tocris Bioscience™ A 196
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Product Code. 18786046
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Product Code. 18786046 Supplier Tocris Bioscience™ Supplier No. 6167/50

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Description

Potent and selective SUV420H1/H2 inhibitor

A 196 is a potent and selective SUV420H1/H2 inhibitor (IC50 values are 25 and 144 nM respectively) that exhibits 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. A 196 inhibits the di- and tri-methylation of H4K20me in multiple cell lines (IC50 < 1 μM).

To request the negative control for A 196, please fill out the SGC 2043 request form on the SGC website.

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Specifications

Chemical Name or Material 6,7-Dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine
CAS 1982372-88-2
Assay Percent Range >98%
Quantity 50 mg
Molecular Formula C18H16Cl2N4
Formula Weight Observed MW: 359.25
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