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  5. Tocris Bioscience™ A 425619

Tocris Bioscience™ A 425619
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Product Code. 18782148
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18782148

Brand: Tocris Bioscience™ 5781/10

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Description

Potent TRPV1 antagonist

A 425619 is a potent TRPV1 antagonist (IC50 = 3-9 nM). Blocks capsaicin-evoked currents in rat DRG neurons and inhibits TRPV1-activation by anandamide (Cat. No. 1339) and N-arachidonoyl-dopamine. Reduces pain in inflammatory, postoperative and osteoarthritic in vivo pain models.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-5-Isoquinolinyl-N′-[[(4-(trifluoromethyl)phenyl]methyl]urea
CAS 581809-67-8
Quantity 10 mg
Target TRPV Antagonists
Molecular Formula C18H14F3N3O
Formula Weight 345.32
Purity >98%
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