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Tocris Bioscience™ Akti-1/2
Potent and selective dual Akt1 and 2 inhibitor
Brand: Tocris Bioscience™ 5773/50
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Description
Akti-1/2 is a potent and selective dual Akt1 and 2 inhibitor (IC50 values are 50 and 210 nM, respectively). Selective for Akt1 and 2 over a panel of other tyrosine and serine/threonine kinases. Sensitizes LnCaP cells to TRAIL (TNF-related apoptosis-inducing ligand) induced apoptosis. Also enhances CAR and TCR retroviral transduction of human T cells. Active in vivo.Specifications
| 1,3-Dihydro-1-[1-[[4-(6-phenyl-1 H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2 H-benzimidazol-2-one | |
| 612847-09-3 | |
| Akt Inhibitor VIII | |
| 50 mg |
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