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Alpelisib, MedChemExpress

Product Code. 16482497
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Product Code. 16482497

Brand: Medchem Express HY15244

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Description

MedChemExpress Alpelisib (BYL-719) is a potent, selective, and orally active PI3Kα inhibitor. Alpelisib (BYL-719) shows efficacy in targeting PIK3CA-mutated cancer. Alpelisib (BYL-719) also inhibits p110α/p110γ/p110δ/p110β with IC50s of 5/250/290/1200 nM, respectively. Antineoplastic activity.

Alpelisib (BYL-719) is a potent, selective, and orally active PI3Kα inhibitor. Alpelisib (BYL-719) shows efficacy in targeting PIK3CA-mutated cancer. Alpelisib (BYL-719) also inhibits p110α/p110γ/p110δ/p110β with IC50s of 5/250/290/1200 nM, respectively. Antineoplastic activity.

Specifications

Chemical Name or Material Alpelisib
CAS 1217486-61-7
Color Off-White
Purity Grade Notes Research
Molecular Formula C19H22F3N5O2S
Quantity 50 mg
Synonym BYL-719
Solubility Information DMSO : 83.33 mg/mL (188.76 mM; Need ultrasonic)
SMILES CC(N=C(S1)NC(N2CCC[C@H]2C(N)=O)=O)=C1C3=CC(C(C)(C(F)(F)F)C)=NC=C3
Molecular Weight (g/mol) 441.47
Formula Weight 441.47
Percent Purity 96.33%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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