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Angiotensin II human, MedChemExpress

Product Code. 16445928
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Product Code. 16445928 Brand Medchem Express Brand No. HY13948

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Description

MedChemExpress Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system.

Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.

Specifications

Chemical Name or Material Angiotensin II human
CAS 4474-91-3
Color White
Purity Grade Notes Research
Molecular Formula C50H71N13O12
Quantity 10 mg
Synonym Angiotensin II Ang II DRVYIHPF
Solubility Information DMSO : 100 mg/mL (95.59 mM; Need ultrasonic) ∣H2O : 50 mg/mL (47.79 mM; Need ultrasonic)
SMILES O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
Molecular Weight (g/mol) 1046.18
Formula Weight 1046.18
Percent Purity 98.16%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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