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Angiotensin II human, MedChemExpress
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.
Specifications
Specifications
| Chemical Name or Material | Angiotensin II human |
| CAS | 4474-91-3 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C50H71N13O12 |
| Quantity | 10 mg |
| Synonym | Angiotensin II Ang II DRVYIHPF |
| Solubility Information | DMSO : 100 mg/mL (95.59 mM; Need ultrasonic) ∣H2O : 50 mg/mL (47.79 mM; Need ultrasonic) |
| SMILES | O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N |
| Molecular Weight (g/mol) | 1046.18 |
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Research purposes only
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