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Tocris Bioscience™ AY 77

Product Code. 18709956
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Quantity:
1 mg
Unit Size:
1mg
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Product Code. 18709956

Brand: Tocris Bioscience™ 7033/1

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This item is not returnable. View return policy

Description

Potent PAR2 biased agonist; exhibits bias for Ca2+ signaling

AY 77 is a potent PAR2 biased agonist. AY 77 exhibits bias for Ca2+ over ERK1/2 signaling (EC50 values are 40 nM for Ca2+ release versus 2 μM for ERK1/2 phosphorylation). Shows selectivity for PAR2 over PAR1. Promotes migration of human breast cancer cells in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Purity 95%
CAS 1835734-92-3
Content And Storage Store at -20°C
Molecular Weight (g/mol) M.W.-observed: 404.5
Quantity 1 mg
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