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Tocris Bioscience™ B02
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Product Code. 18714099
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18714099 5 mg 5mg
18704099 25 mg 25mg
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Product Code. 18714099 Supplier Tocris Bioscience™ Supplier No. 6392/5

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RAD51 recombinase inhibitor

B02 is a RAD51 recombinase inhibitor, exhibiting selectivity for human RAD51 over the E.coli homologue RecA (IC50 values are 27.4 μM and >250 μM, respectively). Inhibits homologous recombination and increases cellular sensitivity to DNA damage in vitro. Enhances the therapeutic effect of cisplatin (Cat. No. 2251) on tumor cells in vivo.
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Specifications

CAS 1290541-46-6
Synonym 3-(Phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone
Quantity 5 mg
Molecular Formula C22H17N3O
Formula Weight 339.4
Purity 98%
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