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  8. Benzyl carbazate, 98+%

Benzyl carbazate, 98+%

Product Code. 11479903
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Product Code. 11479903 Supplier Thermo Scientific Alfa Aesar Supplier No. A13005.06
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Description

CAS: 5331-43-1 | C8H10N2O2 | 166.18 g/mol

Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.

Solubility
Soluble in water (slightly), methanol and DMSO.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Handle under inert gas. Protect from moisture. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 5331-43-1
Molecular Formula C8H10N2O2
Molecular Weight (g/mol) 166.18
MDL Number MFCD00041890
InChI Key RXUBZLMIGSAPEJ-UHFFFAOYSA-N
Synonym benzyl carbazate, benzyl hydrazinecarboxylate, hydrazinecarboxylic acid, phenylmethyl ester, carbobenzoxyhydrazide, carbazic acid, benzyl ester, benzyloxycarbonyl hydrazide, benzylcarbazate, benzyloxy carbonyl hydrazine, n-cbz-hydrazine, unii-h7gm2h55tc
PubChem CID 79242
IUPAC Name benzyl N-aminocarbamate
SMILES C1=CC=C(C=C1)COC(=O)NN

Spezifikation

Melting Point 66°C to 70°C
Quantity 5 g
Beilstein 1952982
Solubility Information Soluble in water (slightly),methanol and DMSO.
Formula Weight 166.18
Percent Purity ≥98%
Chemical Name or Material Benzyl carbazate

RUO – Research Use Only

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