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Bicuculline, MedChemExpress

Product Code. 16474787
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Product Code. 16474787 Supplier Medchem Express Supplier No. HYN0219

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Description

MedChemExpress Bicuculline ((+)-Bicuculline; d-Bicuculline), as a convulsant alkaloid, is a competitive neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+-activated potassium (SK) channels and subsequently blocks the slow afterhyperpolarization (slow AHP) .

Bicuculline ((+)-Bicuculline

Specifications

Chemical Name or Material Bicuculline
CAS 485-49-4
Color White
Purity Grade Notes Research
Molecular Formula C20H17NO6
Quantity 50 mg
Synonym (+)-Bicuculline d-Bicuculline
Solubility Information DMSO : 50 mg/mL (136.11 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C1O[C@@H]([C@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=CC=C(OCO6)C6=C51
Molecular Weight (g/mol) 367.35
Formula Weight 367.35
Percent Purity 98.0%
Grade Research
Physical Form Solid
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