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ACROBiosystems Biotinylated Human IL-4 R alpha / CD124 Protein, Avitag™,His Tag

Product Code. 15847127
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200 μg
25 μg
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200µg
25µg
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15847127 200 μg 200µg
15857127 25 μg 25µg
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Product Code. 15847127 Supplier ACROBiosystems Supplier No. ILRH82E9200UG

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Description

Biotinylated Protein

IL-4 R alpha is also known as IL4R, CD124, IL-4RA.This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema. The binding of IL-4 or IL-13 to the IL-4 receptor on the surface of macrophages results in the alternative activation of those macrophages. Interleukin-4 receptor has been shown to interact with SHC1.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 26.9 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number NP_000409.1
Molecular Weight (g/mol) 26.9 kDa
Quantity 200 μg
Source Biotinylated Human IL-4 R alpha, Avitag,His Tag (ILR-H82E9) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # NP_000409.1).
Immunogen Met 26 - His 232
Storage Requirements -20°C
Gene Alias IL4R,CD124,IL4RA
Common Name IL-4 R alpha
Conjugate Precision Avi
Species Human
Protein Tag His Tag and Avi Tag
Buffer PBS, pH7.4
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype MABSol™ Biotin Labeled Proteins
Purity or Quality Grade >95% as determined by SDS-PAGE
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