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BQ-123, MedChemExpress

Product Code. 16477847
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Product Code. 16477847 Supplier Medchem Express Supplier No. HY12378

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Description

MedChemExpress BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.

Specifications

Chemical Name or Material BQ-123
CAS 136553-81-6
Color White
Purity Grade Notes Research
Molecular Formula C31H42N6O7
Quantity 5 mg
Solubility Information DMSO : 50 mg/mL (81.87 mM; Need ultrasonic)
SMILES O=C(N[C@](C(N(CCC1)[C@]1([H])C2=O)=O)([H])CC(O)=O)[C@H](NC([C@@H](NC([C@H](N2)C(C)C)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34
Molecular Weight (g/mol) 610.7
Formula Weight 610.7
Percent Purity 95.3%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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