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BRD4 degrader AT1, MedChemExpress

Product Code. 16447177
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Product Code. 16447177

Brand: Medchem Express HY111433

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Description

MedChemExpress BRD4 degrader AT1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 as a highly selective Brd4 degrader, with a Kd of 44 nM for Brd4BD2 in cells.

BRD4 degrader AT1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 as a highly selective Brd4 degrader, with a Kd of 44 nM for Brd4BD2 in cells.

Specifications

Chemical Name or Material BRD4 degrader AT1
CAS 2098836-45-2
Color Off-White
Purity Grade Notes Research
Molecular Formula C48H58ClN9O5S3
Quantity 5 mg
Solubility Information DMSO : 100 mg/mL (102.81 mM; Need ultrasonic)
SMILES CC1=C(C)SC2=C1C(C3=CC=C(Cl)C=C3)=N[C@@H](CC(NCCCCCCSC(C)(C)[C@H](NC(C)=O)C(N4[C@@H](C[C@@H](O)C4)C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)=O)=O)C7=NN=C(C)N27
Molecular Weight (g/mol) 972.68
Formula Weight 972.68
Percent Purity 98.69%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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