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Tocris Bioscience™ CC4
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Product Code. 18779708
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18779708

Brand: Tocris Bioscience™ 5236/10

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This item is not returnable. View return policy

Description

High affinity and subtype-selective α6β2 and α4β2 nAChR partial agonist

CC4 is a high affinity and subtype selective α6β2 and α4β2 partial agonist (Ki values are 12 and 26nM for rat α6β2 and α4β2 receptors respectively). Has low affinity for α3β4 and α7 receptors (Ki values are 4.8 and 13 μM for human α3β4 and rat α7 receptors respectively). Stimulates dopamine release from striatal slices in vitro. Attenuates nicotine-induced self-administration and conditional place preference in rats.
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Specifications

Chemical Name or Material (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
CAS 492-02-4
Quantity 10 mg
Target Additional Nicotinic (a4b2) Receptor Compounds
Molecular Formula C24H30N4O2
Formula Weight 406.52
Purity >98%
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