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  4. Invitrogen™ Human CDK9 (Inactive), GST Tag Recombinant Protein

Invitrogen™ Human CDK9 (Inactive), GST Tag Recombinant Protein

Product Code. 15481214
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
10µg
1mg
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Product Code. 15481214

Brand: Invitrogen™ PV6304

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Recombinant full-length human CDK9 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. , Validated in LanthaScreen™ Kinase Binding Assay, Protocols available for simple use and optimized performance, Multiple pack sizes available for convenient use Protein Form: Recombinant The gene accession number for CDK9 (Inactive) is NP_001252.1.

CDK9 is a serine/threonine kinase which when complexed with CyclinT1 forms an active holoenzyme complex. This complex plays a key role in regulating the eukaryotic cell cycle. CDK9 is coexpressed and copurified with CyclinT1. CDK9 regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors. CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation, and viral pathogenesis. The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro. Chronic activation of CDK9 causes cardiac myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P50750
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris HCl with 0.1 mM EDTA, 0.1 mM EGTA, 0.1 mM PMSF, 0.25 mM DTT, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 1025
Molecular Weight (g/mol) 69.1 kDa
Name Human CDK9 (Inactive), GST Tag
Quantity 10 μg
Gene Alias C-2 k; CDC2L4; CDC2-related kinase; Cdk9; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; CTK1; cyclin dependent kinase 9; cyclin-dependent kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); PITALRE; RP11-228B15.5; serine/threonine protein kinase PITALRE; Serine/threonine-protein kinase PITALRE; TAK; Tat-associated kinase complex catalytic subunit
Common Name CDK9
Protein Length 1-372
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Baculovirus
Form Liquid
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