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Thermo Scientific™ CellSensor™ CRE-bla HEK 293T Cell Line

Product Code. 10378123
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Product Code. 10378123 Supplier Thermo Scientific™ Supplier No. K1540

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Description

The CellSensor™ CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE).

The CellSensor™ CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE). To obtain the cell line, the CRE-bla construct was transduced into HEK 293T cells by lentivirus. Subsequent flow cytometry was used to isolate clones responsive to forskolin stimulation. The CellSensor™ CRE-bla HEK 293T cell line can be used to build specific G-protein coupled receptor (GPCR) assays or to detect changes in intracellular cAMP levels. Academic and non-profit customers, please inquire for special pricing.

TRUSTED_SUSTAINABILITY

Specifications

Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Description CellSensor™ CRE-bla HEK 293T Cell Line, 1Vial, ∽ 2,000,000 cells/vial at 2,000,000 cells/mL Quantity of Cells, CRE-bla HEK 293T Cell Line, Fluorescent Detection Method, CellSensor™ Druggable Target, Adherent Growth Properties, Liquid Nitrogen Storage
Detection Method Fluorescent
For Use With (Application) Pharma and biopharma, drug discovery and development, target and lead identification and validation, kinase biology, kinase pathway analysis, pathway biology, cellular pathway analysis assays, cellSensor™ cellular pathway assays
Includes b-lactamase reporter gene under control of the cAMP response element (CRE)
Product Line CellSensor
Quantity 1 Vial
Sample Type CRE-bla HEK 293T
Target Entry PKA, cAMP, cAMP/PKA pathway
Type Cell Line
System Type CellSensor™
Druggable Target Signaling Pathway
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For Research Use Only. Not for use in diagnostic procedures.

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