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STEMCELL Technologies DBZ

Product Code. 17130172
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10 mg
Unit Size:
10mg
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Product Code. 17130172 Supplier STEMCELL Technologies Supplier No. 73092

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Description

Notch pathway inhibitor; Inhibits γ-secretase

  • DBZ is a diazepine inhibitor of γ-secretase, which cleaves transmembrane proteins including Notch, amyloid precursor protein (APP), and Ephrin-B2 (Borgegard et al)
  • DBZ blocks the cleavage of Notch into its active signalling effector, Notch intracellular domain, with an IC50 of 1.7 nM (Milano et al.)

Specifications

CAS 209984-56-5
Synonym Dibenzazepine, YO-01027
Quantity 10 mg
Molecular Formula C26H23F2N3O3
Purity ≥98%
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