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DL-Thioctic acid, 98%, Thermo Scientific™
DL-Thioctic acid, CAS # 1077-28-7, is an antioxidant and coenzyme important for the activity of enzymes.
Brand: Thermo Scientific Alfa Aesar L04711.14
| Quantity | 25g |
|---|
This item is not returnable.
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Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• DL-Thioctic acid derives from octanoic acid, and it has been described as an antioxidant coenzyme important for the activity of enzyme complexes including pyruvate dehydrogenase and glycine decarboxylase
Application
• DL-Thioctic acid has been used in in vivo studies to increase insulin sensitivity and stimulate glucose uptake into adipose and muscle cells in vitro
• DL-Thioctic acid has an essential role in aerobic metabolism
• It has been used as free radical scavenger compound
• It can also assist in repairing oxidative damage via the increase of endogenous antioxidants, including vitamins C, vitamin E, and glutathione
• It can induce apoptosis through caspase-independent and caspase-dependent pathways, a process mediated by intracellular Ca2+
• DL-Thioctic acid has the ability to impact various cellular biological pathways since it can increase glutathione synthesis and modulate transcription factor activity, mainly nuclear factor kappa B (NF-κB)
• It can decrease the phagocytosis of myelin by macrophages
Chemical Identifiers
| C8H14O2S2 | |
| MFCD00005474 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| CHEBI:16494 | |
| OC(=O)CCCCC1CCSS1 |
Specifications
| 1077-28-7 | |
| C8H14O2S2 | |
| 25g | |
| 14,9326 | |
| Soluble in methanol,ethanol,diethyl ether and chloroform. Insoluble in water. | |
| OC(=O)CCCCC1CCSS1 | |
| 206.32 | |
| CHEBI:16494 | |
| 98% |
| 160°C to 165°C | |
| MFCD00005474 | |
| 81853 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| AGBQKNBQESQNJD-UHFFFAOYNA-N | |
| 5-(1,2-dithiolan-3-yl)pentanoic acid | |
| 864 | |
| 206.33 | |
| DL-Thioctic acid |
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