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  4. Invitrogen™ Human DYRK1A, GST Tag Recombinant Protein

Invitrogen™ Human DYRK1A, GST Tag Recombinant Protein

Product Code. 15468533
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Quantity:
10 μg
100 μg
Unit Size:
100µg
10µg
This item is not returnable. View return policy

Product Code. 15468533

Brand: Invitrogen™ PR7189B

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease. DYRK1A catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q13627
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 2mM DTT, 0.5mM EDTA, 150mM NaCl, 0.02% Triton X-100, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 1859
Molecular Weight (g/mol) 113 kDa
Name Human DYRK1A, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 100 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 2310043O08Rik; D16Ertd272e; D16Ertd493e; dual specificity tyrosine phosphorylation regulated kinase 1A; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual specificity YAK1-related kinase; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a; Dyrk; DYRK1; Dyrk1a; ENSMUSG00000074897; Gm10783; hMNB; HP86; mmb; MNB; mnb protein kinase homolog hp86; MNB/DYRK protein kinase; MNBH; MP86; MRD7; OTTHUMP00000109090; Protein kinase minibrain homolog; PSK47; RP86; serine/threonine kinase MNB; serine/threonine-specific protein kinase
Common Name DYRK1A
Gene Symbol DYRK1A
KinaseFamily DYRK Kinase Family
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser⁄Thr Kinases: CMCG Group
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Research Category Drug Discovery, Signal Transduction
Purity or Quality Grade 85% by SDS-PAGE
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