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Tocris Bioscience™ E 64
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Product Code. 18745999
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10 mg
50 mg
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Product Code. Quantity unitSize
18745999 10 mg 10mg
18790288 50 mg 50mg
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Product Code. 18745999

Brand: Tocris Bioscience™ 5208/10

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Potent and irreversible cysteine protease inhibitor

E 64 is a potent and irreversible cysteine protease inhibitor (IC50 values are 1.4, 2.5 and 4.1 nM for cathepsin K, L and S respectively. Also inhibits papain, calpain, cathepsin B and cathepsin H. Has no effect on serine proteases. Reduces HSC-3 tongue cancer cell invasion and induces oxidative stress and apoptosis in filarial parasites. Also inhibits autophagy-associated lysosomal degradation in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type E 64
Purity >98%
Molecular Weight (g/mol) 357.41
Inhibitors E 64

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