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Epiberberine, MedChemExpress

Product Code. 16498898
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
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Product Code. 16498898

Brand: Medchem Express HYN0226

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MedChemExpress Epiberberine is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively.

Epiberberine has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and can be used for the research of Alzheimer disease. Epiberberine inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways. Epiberberinecan be used for the research of diabetic disease.

Specifications

Chemical Name or Material Epiberberine
CAS 6873-09-2
Color orange-Red
Purity Grade Notes Research
Molecular Formula C20H18NO4+
Quantity 10 mg
Solubility Information DMSO : 3.33 mg/mL (9.90 mM; ultrasonic and warming and heat to 60°C)
SMILES COC1=C(OC)C=C2C(CC[N+]3=C2C=C(C=C4)C(C5=C4OCO5)=C3)=C1
Molecular Weight (g/mol) 336.36
Formula Weight 336.36
Percent Purity 98.46%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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