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Thermo Scientific™ EZ-Link™ Psoralen-PEG3-Biotin

Product Code. 10648294 Shop All Thermo Scientific Products
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Quantity:
5 mg
Unit Size:
5mg
Product Code. Quantity unitSize
10648294 5 mg 5mg
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Product Code. 10648294

Brand: Thermo Scientific™ 29986

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Description

Biotinylate DNA or RNA via intercalation and conjugation with thymine- and other pyrimidine-containing bases with this light-activated biotinylation reagent.

Thermo Scientific™ EZ-Link Psoralen-PEG3-Biotin enables biotinylation of DNA or RNA via UV-light-activated intercalation of the psoralen group with thymine- and other pyrimidine-containing bases to form covalent bonds.

Highlights:

  • Water-soluble, polyethylene glycol (PEG) spacer arm
  • Much higher coupling yield than achieved with photoactivatable biotin
  • Psoralen moiety reacts through a cyclo-addition mechanism with the 5,6 double bond in thymine- and other pyrimidine-containing bases
  • Covalent attachment occurs with exposure to UV light (approximately equal to 350nm)
  • Great for biotinylating DNA/RNA probes (∽1 biotin/10-20 bases)
  • Ultrahigh sensitivity relative to radiolabeled probes (<100 femtograms)
  • Does not interfere with hybridization
TRUSTED_SUSTAINABILITY

Specifications

Product Type Psoralen-PEG3-Biotin
Quantity 5 mg
Content And Storage Store at 4°C protected from light and moisture. Shipped at ambient temperature.
Product Line EZ-Link
Cell Permeability Cell-Impermeant
Chemical Reactivity Light-activated
Reactive Moiety Psoralen
Solubility DMF (Dimethylformamide), DMSO (Dimethylsulfoxide), Water
Label or Dye Biotin
Spacer Extra-long, Pegylated
Label Type Biotin & Analogs
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Safety and Handling

compliance-icons
Product Identifier
  • EZ-Link Psoralen-PEG3-Biotin
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash hands thoroughly after handling.
  • P271-Use only outdoors or in a well-ventilated area.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P362+P364-Take off contaminated clothing and wash it before reuse.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : EZ-Link Psoralen-PEG3-Biotin

For Research Use Only. Not for use in diagnostic procedures.

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