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  6. 18055352

Fostriecin sodium salt, Tocris Bioscience™

Product Code. 18055352
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50 μg
Unit Size:
50µg
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18055352 50 μg 50µg
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Product Code. 18055352 Supplier Tocris Bioscience Supplier No. 1840/50U

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Description

Potent PP2A and PP4 inhibitor

Potent inhibitor of protein phosphatase types 2A (PP2A) and 4 (PP4) with IC50 values of 1.5 nM and 3 nM respectively. Also exhibits weaker inhibition of topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM) with no apparent inhibition of protein phosphatase type 2B (PP2B). Active in vivo. Originally identified as an antitumor antibiotic from Streptomyces pulveraceous.
TRUSTED_SUSTAINABILITY

Specifications

CAS 87860-39-7
Molecular Formula C19H26NaO9P
Quantity 50 μg
Synonym fostriecin sodium salt
InChI Key XBUIKNRVGYFSHL-SOAGNPLSSA-M
SMILES CC(C=CC1CC=CC(=O)O1)(C(CC(C=CC=CC=CCO)O)OP(=O)(O)[O-])O.[Na+]
IUPAC Name sodium;[(1Z,3R,4R,6R,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-[(2R)-6-oxo-2,3-dihydropyran-2-yl]trideca-1,7,9,11-tetraen-4-yl] hydrogen phosphate
Molecular Weight (g/mol) 452.372
PubChem CID 124080892
Formula Weight 452.37
Percent Purity >98%
Chemical Name or Material Fostriecin sodium salt
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