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  5. Tocris Bioscience™ GeA-69

Tocris Bioscience™ GeA-69
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Product Code. 18718866
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18718866

Brand: Tocris Bioscience™ 6795/50

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This item is not returnable. View return policy

Description

Selective allosteric PARP14 inhibitor

GeA-69 is a selective allosteric inhibitor of poly (ADP-ribose) polymerase 14 (PARP14) macrodomain 2 (MD2) (IC50 = 720 nM, Kd = 860 nM). It inhibits adenosine diphosphate ribose (ADPR) binding to the macrodomain 2 of PARP14 and prevents PARP14 MD2 localization to DNA damage sites in intact cells. GeA-69 is highly cell permeable.
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Specifications

Chemical Name or Material N-[2-(9 H-Carbazol-1-yl)phenyl]acetamide
CAS 2143475-98-1
Quantity 50 mg
Target PARP
Molecular Formula C20H16N2O
Purity 0.98
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