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Thermo Scientific™ GeneBLAzer™ H2-CRE-bla HEK 293T Cells
Description
GeneBLAzer™ H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor™ CRE-bla HEK293T cell line. CellSensor™ CRE-bla HEK293T cells (Cat. No. K1540) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ H2-CRE-bla HEK293T cells are functionally validated for Z' and EC50 concentrations of Histamine. In addition, GeneBLAzer™ H2-CRE-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The H2 receptor has been implicated in a number of disorders, including peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), dyspepsia, and stress ulcer prophylaxis.
For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
Specifications
Specifications
| Accession Number | BC054510.2 |
| Assay Entry | Cell-based beta lactamase reporter gene |
| Cell State | Dividing Cells |
| Content And Storage | LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol Includes: • GeneBLAzer™ H2-CRE-bla HEK293T cells • GeneBLAzer™ H2-CRE-bla HEK293T Assay Protocol • Certificate of Analysis The GeneBLAzer™ H2-CRE-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
| Description | GeneBLAzer™ H2-CRE-bla HEK 293T Cells, 2 x 106 Cells, ∽2,000,000 cells/vial at 2,000,000 cells/mL Quantity of Cells, 293T (HEK) Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage |
| Detection Method | Fluorescence |
| For Use With (Application) | FRET |
| Gene Symbol | HRH2 |
| Includes | GeneBLAzer™ H2-CRE-bla HEK293T cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: GeneBLAzer™ H2-CRE-bla HEK293T cells, GeneBLAzer™ H2-CRE-bla HEK293T Assay Protocol, Certificate of Analysis |
| Population Status | Single Cell Clone Origin |
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For Research Use Only. Not for use in diagnostic procedures.
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