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Tango™ Tango™ GPR35-bla U2OS Cells

Product Code. 10766875
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Quantity:
1 vial
Unit Size:
Each
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Product Code. 10766875

Brand: Tango™ K1872

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Description

Tango™ GPR35-bla U2OS Cells contain the human G-protein coupled receptor 35 (GPR35) linked to a TEV protease site.

  • Cell Line: U2OS
  • Accession Number: NM_005301.2
  • Cytoplasmic Tail: Native Tail
  • Population Status: Single Cell Clone Origin
  • Tango™ GPR35-bla U2OS cells contain the human G-protein coupled receptor 35 (GPR35) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ GPR35-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Zaprinast. In addition, Tango™ GPR35-bla U2OS cells have been tested for assay performance under variable conditions.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_005301.2
Assay Entry Cell-based beta-arrestin recruitment
Cell State Dividing Cells
Content And Storage Tango™ GPR35-bla U2OS cells cells are shipped on dry ice, 8 x 10^6 cells⁄vial. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Cytoplasmic Tail Native Tail
Detection Method Fluorescence
For Use With (Application) FRET
Human Protein Class G-Protein Coupled Receptor (GPCR)
Population Status Single Cell Clone Origin
Product Line Tango
Quantity 1 vial
Readout End Point
Target Entry GPR35
Cell Line U2OS
System Type Tango™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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