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  5. Tocris Bioscience™ GSK2578215A

Tocris Bioscience™ GSK2578215A
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Product Code. 18747246
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Quantity:
5 mg
25 mg
Unit Size:
25mg
5mg
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Product Code. 18747246

Brand: Tocris Bioscience™ 4629/25

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This item is not returnable. View return policy

Description

Potent, selective LRRK2 inhibitor; brain penetrant

GSK2578215A is a potent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide
CAS 1285515-21-0
Assay Percent Range >99%
Quantity 25 mg
Molecular Formula C24H18FN3O2
Formula Weight Observed MW: 399.42
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